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Since 1957, it has been widely used for various types of cancer, such as colorectal cancer (CRC), breast cancer (BC), and gastric cancer (GC) (26)

In this part of the experiment, we observed that compared with the normal group, the activities of GPx and T-SOD in plasma, prefrontal cortex and hippocampal tissue of rats in the model group were reduced, and the content of MDA was significantly increased, indicating that the oxidative stress level of HE rats increased, which was consistent with previous research results